Research

Research

Long-form, observational analysis of category-level shifts in the women's health economy.

Hormonal

The rise of transition-specific healthcare

Why care models organized around life-stage transitions — not single conditions — are becoming the default in women's health.

The Index Editorial·
6 min read
Why women's health is becoming infrastructure

From a vertical to a structural layer of healthcare: how the category is being rebuilt as infrastructure.

The Index Editorial·
8 min read
The consumerization of preventative care

How at-home diagnostics rewired the entry point to women's healthcare.

The Index Editorial·
5 min read
The future of hormonal health

An observational read on where hormonal health is heading — clinically and structurally.

The Index Editorial·
7 min read
How longevity is reshaping consumer behavior in women's health

The cultural turn toward longevity is changing what women buy, how they screen, and how they relate to clinicians.

The Index Editorial·
6 min read
The formation of the menopause economy

How the menopause category went from invisible to a multi-billion-dollar formation in less than five years.

The Index Editorial·
7 min read
Innovative benefit design for women's health: fewer missed workdays

Integrated Benefits Institute analysis of 1,001 employed US women finds benefit utilization linked to higher retention and 89% job-satisfaction lift.

The Index Editorial·
5 min read
Maternity care deserts across the US — 2024 report

March of Dimes documents counties with no obstetric providers and rising infant mortality in rural and low-income communities.

The Index Editorial·
6 min read
Trends in postpartum depression by race, ethnicity, and prepregnancy BMI

JAMA Network Open serial cross-sectional Kaiser Permanente study finds PPD rates increased across all groups 2010-2021; Black and multiracial women bear highest burden.

The Index Editorial·
7 min read
Prevalence of depression in postmenopausal women: systematic review & meta-analysis

BMC Psychiatry meta-analysis of 50 studies / 385,092 women finds 28.0% pooled global prevalence of depression in postmenopausal women.

The Index Editorial·
6 min read
US maternal mortality 2024 — 17.9 deaths per 100,000 live births

NCHS / CDC Health E-Stat 113: 649 maternal deaths in 2024; Black non-Hispanic rate 44.8 (3.1× White rate); women 40+ at 62.3 per 100,000.

The Index Editorial·
5 min read
Insights into the US maternal mortality crisis: international comparison

Commonwealth Fund: US maternal mortality ratio 22.3 per 100,000 — highest among 18 high-income peers, 10× Norway's rate.

The Index Editorial·
7 min read
Semaglutide in obesity-related HFpEF: sex-stratified efficacy

JACC pooled STEP-HFpEF analysis (n=1,145; 49.7% women): semaglutide produces greater weight loss in women (-9.6%) than men (-7.2%); symptom gains equal.

The Index Editorial·
6 min read
Semaglutide CV outcomes by sex in SELECT (n=17,604)

JACC prespecified sex-stratified analysis: semaglutide 2.4mg consistently reduces MACE in both sexes; women face higher baseline CV risk at equivalent BMI.

The Index Editorial·
6 min read
CheekAge: next-generation buccal epigenetic aging clock

GeroScience publication: Tally Health's CheekAge predicts all-cause mortality and tracks with lifestyle factors via cheek-swab DNA methylation.

The Index Editorial·
5 min read
The Women's Health Initiative randomized trials & clinical practice

JAMA 2024 review synthesizes 20+ years of WHI follow-up: in the timing-hypothesis window (<10 yrs from menopause or <60), MHT shows no significant rise in all-cause mortality and a possible benefit for estrogen-alone in younger women.

The Index Editorial·
8 min read